2 Dec 2024 • A new study has highlighted the critical role of kidney health in cardiovascular disease (CVD) risk prediction.

-Researchers followed 4,742 participants over 5.7 years, uncovering a clear link between changes in renal function—measured as estimated glomerular filtration rate (eGFR)—and CVD events like heart attack and stroke.

• Four eGFR trajectory patterns were identified.

• A gradual decline in kidney function (eGFR trajectory) significantly increased the risk of cardiovascular disease (CVD) in 559 patients, myocardial infarction (MI) in 404 patients, ischemic stroke (IS) in 244 patients, and Heart failure (HF) in 62 patients with hazard ratios (HR) ranging from 1.41 to 1.42.

• Conversely, participants who showed a gradual improvement in kidney function was linked to a reduced risk of CVD (HR 0.40) and MI (HR 0.49).

• These associations were consistent across sensitivity and subgroup analyses, underscoring the critical link between kidney health and cardiovascular outcomes.

The findings emphasize the importance of monitoring kidney health as a potential tool for improving early detection and prevention strategies for cardiovascular diseases, particularly in rural communities.

Source: Annals of Medicine Read Full Story