3 Feb 2025 • A recent study has found that patients with sickle cell disease (SCD) exhibit higher levels of thyroid-stimulating hormone (TSH) compared to healthy individuals (standardized mean difference [SMD] = 1.184).

Though not statistically significant, there was a trend toward lower levels of thyroid hormones, including triiodothyronine (T3), thyroxine (T4), and their free forms. The study also revealed that 4.9% of SCD patients had hypothyroidism, while 8.7% showed signs of subclinical hypothyroidism.

These findings suggest that thyroid abnormalities, especially subclinical hypothyroidism, are more common in SCD patients, underscoring the importance of routine thyroid monitoring to prevent potential progression to overt hypothyroidism and related health issues.

Source: Dovepress | Read Full Story