Hyponatremia in patients with heart failure is often associated with poor short- and long-term outcomes. Its pathogenesis is multidimensional: driven by a synergistic interaction between increased arginine vasopressin (AVP) secretion, sympathetic nervous system activation, and upregulation of the renin-angiotensin-aldosterone system (RAAS), making it pathophysiologically distinct from other forms of hyponatremia and therapeutically challenging to manage.

In this session, Dr. Tushar Shah works through 10 structured clinical questions to help clinicians navigate this complexity - from establishing the correct diagnosis to selecting appropriate correction strategies in the context of ongoing heart failure management.