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Glaucoma Surgery Cuts Recurrence in CMV-Related Uveitis

11 Sept 2025 • A retrospective study of patients with cytomegalovirus-induced anterior uveitis (CMV-AU) found that glaucoma surgery (GS) substantially reduced recurrence compared with antiviral therapy alone.

Key Findings:

  • Over a median 29-month follow-up, recurrence frequency dropped by 77.4% with GS (2.39 to 0.54 episodes/person-year) versus 58.9% with medication only (2.92 to 1.20).
  • Surgically treated patients had a 0.45-fold lower recurrence risk and significantly longer recurrence-free intervals (48.3 vs 20.5 months).
  • However, GS was linked to corneal endothelial cell loss.

These results highlight GS as a powerful strategy to lower CMV-AU recurrence despite potential ocular risks.

Source: BMJ Journals | Read Full Story

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