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Rheumatoid Factor Levels Signal Elevated Risk for Interstitial Lung Disease in RA Patients

6 Aug 2025 • In a study of 4,736 rheumatoid arthritis (RA) patients, rheumatoid factor (RF) positivity was linked to a 50% higher risk of RA-associated interstitial lung disease (RA-ILD) (adjusted OR 1.51).

Post propensity score matching in 1,018 patients, a clear nonlinear relationship emerged, with ILD risk rising sharply beyond an RF threshold of 60 IU/mL.

These findings underscore the need for routine RF monitoring and early ILD screening

Source: Springer Nature Link | Read Full Story

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