21 Nov 2025 • Age at menopause showed a U-shaped relationship with stroke risk in an analysis of 9,159 postmenopausal women.

Each one-year delay in menopause lowered stroke odds by roughly 6% (OR 0.94). But earlier menopause carried marked risk: onset before 45 years more than doubled stroke risk (OR 2.76), while menopause at 45–49 years doubled it (OR 2.08) compared with the 50–55-year group.

Stroke-free survival was also poorer in premature menopause, underscoring menopause timing as a critical cerebrovascular risk marker that may warrant closer preventive vigilance in both early and late transition.

Source: Stroke Journal | Read Full Story