24 Sept 2025 • A study of very low birth weight (VLBW) infants (<1500 g) in the NICU found 16% developed acute kidney injury (AKI, with affected infants showing lower gestational age (25.3 vs. 28.9 weeks) and birth weight (760 g vs. 1060 g).

AKI was associated with prolonged ventilation, vancomycin use, patent ductus arteriosus, necrotizing enterocolitis, and severe intraventricular hemorrhage.

Multivariate analysis identified lower gestational age (OR = 0.70) and prolonged inotrope therapy ≥3 days (OR = 6.13) as independent risk factors.

Findings highlight hypotension as a major driver, stressing the importance of close hemodynamic monitoring and early risk stratification in preterm infants.

Source: Wiley Online Library | Read Full Story