15 Aug 2025 • Analysis of >48,000 participants from NHANES and ELSA found depression strongly linked to higher asthma risk.

Key Findings:

• Depression nearly doubled asthma odds in NHANES (OR = 2.00) and raised odds by 75% in ELSA, even after adjustments.
• Genetic analysis showed a significant positive correlation, and Mendelian randomization confirmed a causal effect (OR = 1.29) with no reverse causality.

The association persisted after adjusting for smoking, drinking, and education, suggesting that managing depression may help prevent asthma and support integrated mental–respiratory health strategies.

Source: BMC Psychiatry | Read Full Story