12 Sept 2025 • In a study of preterm infants (<32 weeks), red blood cell (RBC) transfusion frequency was independently and dose-dependently linked to bronchopulmonary dysplasia (BPD).

Key Findings:

• Infants who developed BPD received more transfusions on average (4.24 vs 1.89), and each additional transfusion raised BPD risk (OR 1.245).
• Receiving ≥4 transfusions strongly predicted both higher risk and severity of BPD (AUC 0.749).
• Lower gestational age and hemoglobin levels were associated with greater transfusion needs.

These findings highlight that minimizing unnecessary transfusions and optimizing anemia management may reduce BPD risk in vulnerable preterm infants.

Source: BMC Pediatrics | Read Full Story