29 May 2025 • Pregnant women with primary Sjögren's syndrome (pSS) face a higher risk of having newborns with heart conditions (29%).

Key Findings:

• Affected infants also had increased rates of preterm birth, low birth weight, asphyxia, brain injury, and infections.
• Key maternal risk factors included umbilical cord issues, low C3/C4 levels, preterm labor, and immunosuppressant use.
• Higher pSS disease activity significantly raised neonatal heart disease risk (OR 1.503).

Findings call for close monitoring and multidisciplinary care in pSS pregnancies.

Source: Oxford Academic | Read Full Story