3 Jun 2025 • A comprehensive meta-analysis of over 2,000 Crohn’s disease patients found that non-invasive tests like fecal calprotectin and imaging methods—including CT/MR enterography (CTE/MRE) and intestinal ultrasound (IUS)—offer high sensitivity for detecting postoperative disease recurrence.

Fecal calprotectin (<50 μg/g) showed 0.76 sensitivity and 0.66 specificity, while CT/MR enterography and intestinal ultrasound (IUS) showed high sensitivity (89-92%) and moderate specificity (0.65), which improved to 85% with optimized radiographic parameters.

These findings support using non-invasive tools for monitoring Crohn’s recurrence and guiding treatment decisions.

Source: CGH Journal | Read Full Story