A study in older adults with type 2 diabetes found that renal dysfunction significantly raises the risk of vertebral fractures (VFs). 

**Key Findings:**
- Patients with either estimated glomerular filtration rate decline or proteinuria had nearly double the risk (HR = 1.98), while those with both had over 2.5 times the risk (HR = 2.53). 
- Low bone CT attenuation (HU) also predicted VFs. 
- Adding renal dysfunction to prediction models improved accuracy (AUC from 0.817 to 0.839). 

Risk was notably higher in women and those without neuropathy, vascular disease, or insulin use.

Source: Dovepress | [Read Full Story](https://www.dovepress.com/associations-between-renal-dysfunction-subtypes-and-vertebral-fracture-peer-reviewed-fulltext-article-DMSO)