22 Jul 2025 • A study of 1,361 pregnant women found remnant cholesterol (RC) to be a strong early predictor of gestational diabetes (GDM), independent of triglycerides (TG).

Key Findings:

• GDM occurred in 25.9%, with each unit rise in RC raising risk by 5% (OR 1.05).
• Women in the highest RC quartile had over double the risk (OR 2.27), showing a clear dose–response trend.
• High RC predicted GDM even with low TG, while high TG alone was not significant. RC outperformed traditional lipids (AUC 0.687) and was strongly associated with fasting hyperglycemia-driven GDM, highlighting its value for early screening.

Source: BMC Pregnancy and Childbirth | Read Full Story