28 May 2025 • A large-scale study reveals a strong and early link between sleep disorders and neurodegenerative diseases (NDDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis, and various dementias.

Sleep disorders—particularly insomnia and sleep apnea were associated with significantly increased risks (HRs ranging from 1.15 to 5.11). Recurrent sleep disorders further amplified risk, especially for vascular dementia (HR up to 3.25).

These findings highlight the critical need to address treatable sleep issues as a potentially modifiable pathway to reduce long-term neurodegenerative risk, even in genetically low-risk individuals.

Source: Nature | Read Full Story