10 Apr 2025 • In a randomized trial of neonates <29 weeks’ gestation, adding multimodal hemodynamic monitoring targeted echocardiography and cerebral near-infrared spectroscopy to standard care did not significantly lower vasoactive-ventilation-renal (VVR) scores at day 7 (16.5 vs 18.9).

No infants in the multimodal group hit critically high VVR scores (>95th percentile) vs 11.1% in standard care.

Importantly, BPD incidence was significantly reduced (41.3% vs 59.0%), suggesting potential for preventing severe outcomes despite no short-term VVR improvement.

Source: JAMA Network | Read Full Story