22 Jan 2025 • Research spanning nearly two decades involving over 1.5 million individuals has found that long-term aspirin use considerably reduces cancer risk and mortality.

• Aspirin users had an 8% lower cancer risk and a 20% lower cancer mortality rate compared to non-users.
• Stronger chemopreventive effects were observed among those who used aspirin for more than 10 years, showing strong risk reductions for lung, breast, and colorectal cancers, but not for bladder cancer and leukaemia.
• The findings suggest that initiation of low-dose aspirin at ages as young as 40 could help protect against cancer.