28 Oct 2025 • Unrecognized myocardial infarction (UMI) carried a markedly worse long-term prognosis, particularly in men, new data from the Rotterdam Study showed.

Men with UMI faced elevated risks of heart failure (HR 1.90), atrial fibrillation (HR 1.91), and stroke (HR 2.06), along with 59% higher all-cause mortality.

Similarly, higher risks were seen with recognized MI (HR 2.49 for heart failure, HR 1.79 for atrial fibrillation, HR 1.36 for stroke, and HR 1.63 for all-cause mortality).

In women, UMI showed smaller increases in heart failure (HR 1.31) and mortality (HR 1.21), which were attenuated after adjusting for cardiovascular risk factors.

The results highlight that unrecognized MI poses significant long-term cardiovascular and mortality risks, underscoring the need for early detection and preventive strategies.

Source: Oxford Academic | Read Full Story