29 Jan 2026 • Adults diagnosed with idiopathic non-infectious uveitis faced a striking increase in glaucoma risk.

In a study of more than 33,000 patients, uveitis was associated with a ninefold higher risk of incident glaucoma (HR 9.63). Risk peaked early, surging more than 30-fold within the first year after diagnosis (HR 33.78). Elevated risk was seen across glaucoma subtypes, including primary open-angle glaucoma (HR 4.47), primary angle-closure glaucoma (HR 11.55), and steroid-induced glaucoma, which showed the strongest association (HR 51.29). Panuveitis also carried an exceptionally high risk (HR 50.49).

Younger adults were disproportionately affected, with patients aged 18–49 years experiencing a 36-fold increase in glaucoma risk (HR 36.65). Use of systemic corticosteroids (HR 10.19) and topical ophthalmic steroids (HR 5.67) further amplified risk.

The findings identify non-infectious uveitis as a powerful driver of secondary glaucoma.

Source: Science Direct | Read full story