1 Sept 2025 • In patients with type 2 diabetes, higher nocturnal hypoxemic burden—measured as time spent with oxygen saturation <90% (T90)—was strongly linked to future kidney decline.

Those in the highest T90 quartile had nearly a threefold greater risk of developing very-high-risk chronic kidney disease (CKD) compared to the lowest quartile (OR 2.96), independent of traditional risk factors.

Progression to severe CKD occurred in 15% of high T90 patients versus 6.2% in others, underscoring nocturnal hypoxemia as a powerful and novel prognostic marker for diabetic kidney disease progression.

Source: BMC | Read Full Story