26 May 2025 • In a nationwide study of 4.4 million adults, steatotic liver disease (SLD) was significantly linked to increased risk of systemic sclerosis (SSc).

Key Findings:

• Individuals with metabolic dysfunction-associated liver disease (MASLD) had a 61% higher risk (aHR: 1.612), while alcohol-related liver disease (ALD) carried over a threefold risk (aHR: 3.063) of SSc.
• Metabolic dysfunction ALD also showed elevated risk (aHR: 1.575).

Findings highlight the need for integrated monitoring of liver and autoimmune health, especially through alcohol reduction strategies.

Source: Oxford Academic | Read Full Story